Since version 10.5 “Leopard”, Mac OS X has had DTrace, a tool used for performance analysis and troubleshooting. It provides data for Apple’s Instruments tool, as well as a collection of command line tools that are implemented as DTrace scripts. I’m familiar with the latter as I wrote the originals for the DTraceToolkit, which Apple then customized and enhanced for Mac OS X where they are shipped by default (great!). I use them regularly to answer this question:

why is my MacBook slow?

I work in an office where everyone has MacBook Pros, and “why is my MacBook slow?” is a common question. Applications can become slow or unresponsive while waiting for CPU work, memory requests or disk I/O to complete.

via Brendan's blog » Top 10 DTrace scripts for Mac OS X.